Therapeutic Advances in Inflammatory Bowel Disease: Current Therapies and Future Directions

Released on by Giulia Roda
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  • Therapeutic Advances in Inflammatory Bowel Disease: Current Therapies and Future Directions Book Detail

  • Author : Giulia Roda
  • Release Date : 2023-10-23
  • Publisher : Frontiers Media SA
  • Genre : Medical
  • Pages : 150
  • ISBN 13 : 2832536662
  • File Size : 67,67 MB
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Therapeutic Advances in Inflammatory Bowel Disease: Current Therapies and Future Directions by Giulia Roda PDF Summary

Book Description: Inflammatory bowel diseases (IBD), are chronic and progressive diseases. Long-term complications are demolition surgery and colon-rectal cancer (CRC). A treat-to-target approach aims to modify the natural course of these diseases. Targets are pre-defined therapeutic goals demonstrated to prevent end-organ disfunction and disability in the long-term period. According to the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) indications, mucosal healing (MH) and clinical remission are the main targets in IBDs. Recently, the concept of remission and evidence on new targets included histological remission and transmural healing as future new targets. It remains controversial whether achieving these targets is associated with significantly better long-term disease outcomes. In this Research Topic, we aim to systematically review current evidence and future perspectives on therapeutic targets in IBD including mucosal and transmural healing.

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