Biological Basis of Detoxication

preview-18
  • Biological Basis of Detoxication Book Detail

  • Author : John Caldwell
  • Release Date : 2012-12-02
  • Publisher : Elsevier
  • Genre : Nature
  • Pages : 444
  • ISBN 13 : 0323150101
  • File Size : 13,13 MB

Biological Basis of Detoxication by John Caldwell PDF Summary

Book Description: Biological Basis of Detoxication focuses on the biological processes involved in detoxication, with emphasis on the biochemistry of the removal of xenobiotics from an organism. Topics range from the formation of toxic metabolites and compounds that are not metabolized at all to the tissue distribution and nutritional considerations, the kinetics and mechanisms of the metabolic and excretory processes, and the integration of xenobiotic metabolism in the activation and detoxication of carcinogens. Organized into 14 chapters, this book begins with an overview of the enzymatic basis for the metabolic activation of foreign compounds in forming reactive chemical intermediates. The first few chapters discuss the identification of reactive electrophiles derived from xenobiotics, intratissue distribution of activating and detoxicating enzymes, enzymatic and non-enzymatic modes of xenobiotic metabolism, and unmetabolized compounds. The middle chapters explore the biological basis of detoxication of oxygen free radicals, physiologic and kinetic aspects of the fate of xenobiotics, excretion of xenobiotics, and effects of nutrition on detoxication. The remaining chapters look at the relationships between the enzymes of detoxication and host defense mechanisms, metabolic basis of target organ toxicity, the enzymatic factor in selective toxicity, and intraindividual and interindividual variations in rates of hepatic metabolism of exogenous chemicals. Pharmacologists, toxicologists, and biochemists will find this book highly informative.

Disclaimer: www.yourbookbest.com does not own Biological Basis of Detoxication books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Biological Basis of Detoxication

Biological Basis of Detoxication

File Size : 32,32 MB
Total View : 3398 Views
DOWNLOAD

Biological Basis of Detoxication focuses on the biological processes involved in detoxication, with emphasis on the biochemistry of the removal of xenobiotics f

Angiogenesis: In Vitro Systems

Angiogenesis: In Vitro Systems

File Size : 44,44 MB
Total View : 1402 Views
DOWNLOAD

Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modu

Current Catalog

Current Catalog

File Size : 21,21 MB
Total View : 4907 Views
DOWNLOAD

First multi-year cumulation covers six years: 1965-70.