Antifolate Drugs in Cancer Therapy

preview-18
  • Antifolate Drugs in Cancer Therapy Book Detail

  • Author : Ann L. Jackman
  • Release Date : 1999-01-22
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 769
  • ISBN 13 : 1592597254
  • File Size : 83,83 MB

Antifolate Drugs in Cancer Therapy by Ann L. Jackman PDF Summary

Book Description: In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an important class of anticancer drugs. The distinguished contributors discuss the preclinical and clinical pharmacology of methotrexate, other dihydrofolate reductase inhibitors, 5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death. The wide and progressive scope of Antifolate Drugs in Cancer Therapy provides entré to exciting new avenues for future research, and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.

Disclaimer: www.yourbookbest.com does not own Antifolate Drugs in Cancer Therapy books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Antifolate Drugs in Cancer Therapy

Antifolate Drugs in Cancer Therapy

File Size : 57,57 MB
Total View : 6876 Views
DOWNLOAD

In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an

Medicinal Chemistry of Anticancer Drugs

Medicinal Chemistry of Anticancer Drugs

File Size : 24,24 MB
Total View : 4630 Views
DOWNLOAD

Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing o

Encyclopedia of Malaria

Encyclopedia of Malaria

File Size : 67,67 MB
Total View : 9153 Views
DOWNLOAD

The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significa

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism

File Size : 86,86 MB
Total View : 3752 Views
DOWNLOAD

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow can

Research on Melanoma

Research on Melanoma

File Size : 73,73 MB
Total View : 695 Views
DOWNLOAD

The book Research on Melanoma: A Glimpse into Current Directions and Future Trends, is divided into sections to represent the most cutting-edge topics in melano