Asymmetric Synthesis Of 3, 3-disubstituted Oxindoles

Released on by Dalpozzo Renato
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  • Asymmetric Synthesis Of 3, 3-disubstituted Oxindoles Book Detail

  • Author : Dalpozzo Renato
  • Release Date : 2019-09-11
  • Publisher : World Scientific
  • Genre : Science
  • Pages : 320
  • ISBN 13 : 1786347318
  • File Size : 48,48 MB
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Asymmetric Synthesis Of 3, 3-disubstituted Oxindoles by Dalpozzo Renato PDF Summary

Book Description: Indole derivatives are the most common heterocycle compounds present in nature, for this reason, they have been referred to as 'privileged structures'. In fact, many approved drugs — and natural products — belong to this family. Among indole derivatives, oxindoles have a structural complexity, which have stimulated generations of synthetic chemists to design strategies for assembling these structures, and their enantioselective synthesis is still growing.This book proposes to describe the known enantioselective syntheses of oxindole derivatives. It is divided in six chapters each referring to a specific class of asymmetric oxindole derivatives. After the introduction, Chapter 2 describes all-carbon spirooxindoles; Chapter 3, open chain 3,3-dialkyloxindoles; Chapter 4, 3-substituted-3-aminooxindoles; Chapter 5, 3-substituted-3-hydroxyoxindoles; Chapter 6, 3-hetero-3-substituted oxindoles. It will be a useful tool for synthetic chemists, who assemble total synthesis of natural products, as well as for drug discovery chemists either in academic or in industry R&S laboratories.

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Functional diversity and molecular architecture in biologically active oxindoles. Transition metal-catalyzed intramolecular Heck reactions and amide alpha-aryla

Studies in Natural Products Chemistry

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Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modu