Cross-Coupling Reactions

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  • Cross-Coupling Reactions Book Detail

  • Author : Norio Miyaura
  • Release Date : 2003-07-01
  • Publisher : Springer
  • Genre : Science
  • Pages : 253
  • ISBN 13 : 354045313X
  • File Size : 56,56 MB

Cross-Coupling Reactions by Norio Miyaura PDF Summary

Book Description: In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of “metal-catalyzed organic syntheses”. An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).

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Cross-Coupling Reactions

Cross-Coupling Reactions

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In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon

Applied Cross-Coupling Reactions

Applied Cross-Coupling Reactions

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“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications

Copper-Mediated Cross-Coupling Reactions

Copper-Mediated Cross-Coupling Reactions

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Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date coll

Cross-coupling Reactions

Cross-coupling Reactions

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"Cross-Coupling Reactions: An Overview opens with an overview of the fundamentals and applications of the young and fast developing area of transition metal cat

Advances in Cross-Coupling Reactions

Advances in Cross-Coupling Reactions

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In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. T