Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Released on by H.Gerhard Vogel
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  • Drug Discovery and Evaluation: Methods in Clinical Pharmacology Book Detail

  • Author : H.Gerhard Vogel
  • Release Date : 2010-12-15
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 576
  • ISBN 13 : 3540898905
  • File Size : 72,72 MB
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Drug Discovery and Evaluation: Methods in Clinical Pharmacology by H.Gerhard Vogel PDF Summary

Book Description: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

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Drug Discovery and Evaluation

Drug Discovery and Evaluation

File Size : 85,85 MB
Total View : 7581 Views
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This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, inc

Drug Discovery and Evaluation

Drug Discovery and Evaluation

File Size : 9,9 MB
Total View : 9483 Views
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This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, inc