Epithelial-Mesenchymal Plasticity in Cancer Metastasis

Released on by Mohit Kumar Jolly
preview-18

  • Epithelial-Mesenchymal Plasticity in Cancer Metastasis Book Detail

  • Author : Mohit Kumar Jolly
  • Release Date : 2020-12-29
  • Publisher : MDPI
  • Genre : Medical
  • Pages : 512
  • ISBN 13 : 3039367242
  • File Size : 73,73 MB
DOWNLOAD BOOK

Epithelial-Mesenchymal Plasticity in Cancer Metastasis by Mohit Kumar Jolly PDF Summary

Book Description: Recent studies have highlighted that epithelial-mesenchymal transition (EMT) is not only about cell migration and invasion, but it can also govern many other important elements such as immunosuppression, metabolic reprogramming, senescence-associated secretory phenotype (SASP), stem cell properties, therapy resistance, and tumor microenvironment interactions. With the on-going debate about the requirement of EMT for cancer metastasis, an emerging focus on intermediate states of EMT and its reverse process mesenchymal-epithelial transition (MET) offer new ideas for metastatic requirements and the dynamics of EMT/MET during the entire metastatic cascade. Therefore, we would like to initiate discussions on viewing EMT and its downstream signaling networks as a fulcrum of cellular plasticity, and a facilitator of the adaptive responses of cancer cells to distant organ microenvironments and various therapeutic assaults. We hereby invite scientists who have prominently contributed to this field, and whose valuable insights have led to the appreciation of epithelial-mesenchymal plasticity as a more comprehensive mediator of the adaptive response of cancer cells, with huge implications in metastasis, drug resistance, tumor relapse, and patient survival.

Disclaimer: www.yourbookbest.com does not own Epithelial-Mesenchymal Plasticity in Cancer Metastasis books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.