Folded Synthetic Peptides for Biomedical Applications

Released on by Alessandro Contini
preview-18

  • Folded Synthetic Peptides for Biomedical Applications Book Detail

  • Author : Alessandro Contini
  • Release Date : 2019-09-26
  • Publisher : Frontiers Media SA
  • Genre :
  • Pages : 145
  • ISBN 13 : 2889630455
  • File Size : 11,11 MB
DOWNLOAD BOOK

Folded Synthetic Peptides for Biomedical Applications by Alessandro Contini PDF Summary

Book Description: Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequential arrangement, induce secondary structures peptides. Such building blocks include D- and other non-proteinogenic amino acids, as well as beta- and gamma-amino acids. This Research Topic comprises a collection of papers by an international group of 77 scientists with a background in synthetic, analytical, computational and medicinal chemistry, as well as in biochemistry and pharmacology. Their research is presented here in a total of 11 papers (8 original research reports and 3 reviews), covering diverse aspects of folded synthetic peptides. These studies include the preparation and characterization of new peptide monomers with interesting folding properties, the synthesis and conformational analysis of non-natural peptides, as well as the use of folded peptidomimetics as molecular switches. Additionally, a range of biomedical applications, such as antimicrobial, anti-inflammatory, antiangiogenic and immune-stimulating activities, are also reported. We hope this eBook will be a source of inspiration and knowledge for scientist in various disciplines related to folded peptides and their many applications, as well as for those who want to learn more about this fascinating field of research.

Disclaimer: www.yourbookbest.com does not own Folded Synthetic Peptides for Biomedical Applications books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Biologically Active Peptides

Biologically Active Peptides

File Size : 60,60 MB
Total View : 5729 Views
DOWNLOAD

Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.