Imaging of Prompt Gamma Emissions During Proton Therapy for Geometric and Dosimetric Verification: Nptool Simulation

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  • Imaging of Prompt Gamma Emissions During Proton Therapy for Geometric and Dosimetric Verification: Nptool Simulation Book Detail

  • Author : Andrew Boston
  • Release Date : 2017
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  • File Size : 34,34 MB
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Imaging of Prompt Gamma Emissions During Proton Therapy for Geometric and Dosimetric Verification: Nptool Simulation by Andrew Boston PDF Summary

Book Description: The Gamma Ray Imaging (GRI+) Compton camera at the University of Liverpool is investigated for its suitability for range and dose verification of Proton Therapy (PT). The verification is done by measuring the prompt gamma emissions (PG) during treatment; providing the advantage of online treatment verification[1]. The simulation will be tested against measurements at Clatterbridge Cancer Centre (CCC), where 60 MeV proton beam is used for treatment of eye cancer, and is aimed to be applicable at higher proton beam energies.[2]The PG emitted following inelastic scattering of the proton off target nuclei are in the high energy region ranging from 2 to 10 MeV. Optimisation of the GRI+ set up for the measurement of high energy gamma rays is being performed by using simulation and laboratory measurements prior to clinical measurements at the CCC. This poster will report on the characterisation of the GRI+ Compton Camera using Monte Carlo simulation. A code written in the NPTool framework based on the Geant4 and Root packages is used. Preliminary results are presented.[3]1.t C. Min et al. Prompt gamma measurements for locating the dose falloff region in the proton therapy. APPLIED PHYSICS LETTERS, 89(18), OCT 30 2006.2.t A. Kacperek. Dose verification by activation in vivo following proton beam eye radiotherapy. Journal of Radioanalytical and Nuclear Chemistry, 271(3):731u2013 740, Mar 2007.3.t A. Matta et al. NPTool: a simulation and analysis framework for low-energy nuclear physics experiments. JOURNAL OF PHYSICS G-NUCLEAR AND PARTICLE PHYSICS, 43(4), APR 2016.

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