Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Released on by Ragu Ramanathan
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  • Mass Spectrometry in Drug Metabolism and Pharmacokinetics Book Detail

  • Author : Ragu Ramanathan
  • Release Date : 2011-09-20
  • Publisher : John Wiley & Sons
  • Genre : Science
  • Pages : 326
  • ISBN 13 : 111821157X
  • File Size : 94,94 MB
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Mass Spectrometry in Drug Metabolism and Pharmacokinetics by Ragu Ramanathan PDF Summary

Book Description: This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.

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Mass Spectrometry in Drug Metabolism

Mass Spectrometry in Drug Metabolism

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When a dose of drug is administered, three main phases of drug action may be distingushed. In the "pharmaceutical" phase the dosage form disintegrates, the acti