Metabolite Safety in Drug Development

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  • Metabolite Safety in Drug Development Book Detail

  • Author : Suzanne L. Iverson
  • Release Date : 2016-07-05
  • Publisher : John Wiley & Sons
  • Genre : Science
  • Pages : 351
  • ISBN 13 : 1118949668
  • File Size : 90,90 MB

Metabolite Safety in Drug Development by Suzanne L. Iverson PDF Summary

Book Description: A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA. • Reviews the analytical techniques and experimental designs critical for metabolite studies • Covers methods including chirality, species differences, mass spectrometry, radiolabels, and in vitro / in vivo correlation • Discusses target pharmacology, in vitro systems aligned to toxicity tests, and drug-drug interactions • Includes perspectives from authors with firsthand involvement in industry and the study of drug metabolites, including viewpoints that have influenced regulatory guidelines

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Metabolite Safety in Drug Development

Metabolite Safety in Drug Development

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A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for

Metabolite Safety in Drug Development

Metabolite Safety in Drug Development

File Size : 55,55 MB
Total View : 7450 Views
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"This book focuses on the characterization of metabolites once a drug candidate is selected, featuring case studies to illustrate lessons learned and a perspect