Cyclic Nucleotides

preview-18
  • Cyclic Nucleotides Book Detail

  • Author : P. D. Kebabian
  • Release Date : 2012-12-06
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 907
  • ISBN 13 : 3642683932
  • File Size : 13,13 MB

Cyclic Nucleotides by P. D. Kebabian PDF Summary

Book Description: Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists. Pharmacology is a science that among other things investigates chemical compounds that affect the physiology of cells, tissues and organs. Frequently pharmacologists account for the effect of low concentrations of a drug upon a tissue by invoking the presence of a receptor upon the surface of the cell. Traditional pharmacologists excelled at identifying and classifying the properties of receptors. A. J. CLARK'S monograph in the earlier series of the Handbook of Experimental Pharmacology (CLARK 1937) summarized the mathematics underlying the traditional pharmacological approach towards receptors. By its nature, however, classic pharmacology provided little useful information about the intracellular events occurring as a consequence of occupying a receptor; for example, ALQUIST (1948) identified the beta-adrenocep tor, but he did not provide any insight into how stimulation of the receptor produces tissue-specific physiological responses. The discovery of cyclic AMP by RALL and SUTHERLAND (see RALL, Vol. I) led to biochemical investigations of many different receptors (including ALQUIST'S beta-adrenoceptor) that share a cyclic nucleotide as a common factor in the biochemical mechanisms that translate the occupancy of receptors into physiological effects. Ten years ago, in the introduction to their monograph on cyclic nucleotides, ROBISON et al. (1971) commented on the rapid growth of interest in cyclic nucleotides over the preceding years.

Disclaimer: www.yourbookbest.com does not own Cyclic Nucleotides books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Cyclic Nucleotides

Cyclic Nucleotides

File Size : 11,11 MB
Total View : 1484 Views
DOWNLOAD

Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry o

The Fight: Prince Vs. Michael Jackson

The Fight: Prince Vs. Michael Jackson

File Size : 36,36 MB
Total View : 7587 Views
DOWNLOAD

The work Michael Jackson and the Ghost of Ben is about Michael Jackson discovering that his pet rat, named Ben, has died, and therefore, the King of Pop discuss

On Time

On Time

File Size : 8,8 MB
Total View : 5520 Views
DOWNLOAD

A memoir by Morris Day of The Time centering around his lifelong relationship and association with Prince"A vital, illuminating, and wildly entertaining autobio

Untouchable

Untouchable

File Size : 34,34 MB
Total View : 3713 Views
DOWNLOAD

The investigative biography of Michael Jackson’s final years: “A tale of family, fame, lost childhood, and startling accusations never heard before” (ABC