Molecular Biology of Metal Homeostasis and Detoxification

Released on by Markus J. Tamás
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  • Molecular Biology of Metal Homeostasis and Detoxification Book Detail

  • Author : Markus J. Tamás
  • Release Date : 2006-07-07
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 519
  • ISBN 13 : 3540317198
  • File Size : 78,78 MB
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Molecular Biology of Metal Homeostasis and Detoxification by Markus J. Tamás PDF Summary

Book Description: One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

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