Protocols in Human Molecular Genetics

Released on by Christopher G. Mathew
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  • Protocols in Human Molecular Genetics Book Detail

  • Author : Christopher G. Mathew
  • Release Date : 2008-02-03
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 461
  • ISBN 13 : 1592594964
  • File Size : 76,76 MB
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Protocols in Human Molecular Genetics by Christopher G. Mathew PDF Summary

Book Description: Extraordinary advances have been made in the field of human molecular genetics during the past five years. The ability to amplify a specific region ofDNA a millionfold in a few hours using the polymerase chain reaction has led to the rapid identification of mutations in human disease and of DNA sequence polymorphisms on every human chro- some. DNA fragments of up to 1 megabase in length can now be resolved by pulsed-field gel electrophoresis to create long-range physical maps of important regions of the genome, and can be cloned in the form of yeast artificial chromosomes. The discovery of highly variable "minisatellite" DNA sequences has led to the development of DNA fingerprinting. The application of these techniques to the study of the human genome has culminated in major advances such as the cloning of the cystic fibrosis gene, the construction of genetic linkage maps of each human chro- some, the mapping of many genes responsible for human inherited d- orders, genetic fingerprinting of forensic specimens, and the detection of mutations involved in the development of human tumors. Although many of the new techniques in molecular genetics can be learned relatively easily, it is often difficult for a researcher to obtain all of the relevant information necessary for getting up a technique and applying it successfully. The information available in the research lite- ture often lacks the depth of description that the new user requires.

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Protocols in Human Molecular Genetics

Protocols in Human Molecular Genetics

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Extraordinary advances have been made in the field of human molecular genetics during the past five years. The ability to amplify a specific region ofDNA a mill

Current Protocols in Human Genetics

Current Protocols in Human Genetics

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Current Protocols in Human Genetics, a two-volume looseleaf manual, is the one publication needed for comprehensive coverage of the latest methods in human gene

Human Molecular Genetics

Human Molecular Genetics

File Size : 94,94 MB
Total View : 5102 Views
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Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental proc