Synthesis of Therapeutic Oligonucleotides

Released on by Satoshi Obika
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  • Synthesis of Therapeutic Oligonucleotides Book Detail

  • Author : Satoshi Obika
  • Release Date : 2018-12-08
  • Publisher : Springer
  • Genre : Medical
  • Pages : 284
  • ISBN 13 : 981131912X
  • File Size : 93,93 MB
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Synthesis of Therapeutic Oligonucleotides by Satoshi Obika PDF Summary

Book Description: This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential. Nucleic acid-based therapeutics are attracting much attention, and numerous therapeutic oligonucleotides, such as antisense oligonucleotides, siRNAs, splice-switching oligonucleotides, and nucleic acid aptamers, are being evaluated in clinical trials for the treatment of a variety of diseases. Synthesis of Therapeutic Oligonucleotides covers a broad range of topics in the field that are of high relevance to researchers, including the synthesis of natural and chemically modified oligonucleotides, the development of novel nucleic acid analogs, industrial scale synthesis and purification of oligonucleotides, and important aspects of chemistry, manufacturing, and controls (CMC). The aim is to provide new insights and inspire fresh ideas in nucleic acid chemistry that may ultimately lead to novel concepts and techniques and the discovery of more effective nucleic acid drugs. The book will be of high value for both established researchers in the field and students intending to specialize in nucleic acid chemistry research.

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Synthesis of Therapeutic Oligonucleotides

Synthesis of Therapeutic Oligonucleotides

File Size : 14,14 MB
Total View : 9861 Views
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This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potenti

Modified Nucleic Acids

Modified Nucleic Acids

File Size : 27,27 MB
Total View : 2794 Views
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This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical