Serotonin Receptors and their Ligands

preview-18
  • Serotonin Receptors and their Ligands Book Detail

  • Author : B. Olivier
  • Release Date : 1997-07-10
  • Publisher : Elsevier
  • Genre : Science
  • Pages : 379
  • ISBN 13 : 0080541119
  • File Size : 43,43 MB

Serotonin Receptors and their Ligands by B. Olivier PDF Summary

Book Description: An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists.Structure - affinity relationships and structure - activity relationships of agonists, partial agonists, and antagonists of 5-HT receptors and uptake sites, are discussed. Structure, sequence homology and the effect of site-directed mutations of 5-HT receptors and the reuptake site on the binding of ligands show the tremendous impact of molecular biology on medicinal chemistry research. Also discussed is the pharmacology and (potential) clinical applications of ligands for the 5-HT receptors and the reuptake site. By developing elegant techniques of cloning and expression of serotonin receptor subtypes, their mutants and chimeras, a unique opportunity was offered to study the binding mode of serotoninergic ligands to their receptors and transporters.The distribution, structure and homologies of serotonin receptor subtypes and the structure of the serotonin transporter are also taken into account.The (potential) therapeutic applications of ligands of the different subtypes are described.Altogether an excellent addition to the Pharmacochemical Library series.

Disclaimer: www.yourbookbest.com does not own Serotonin Receptors and their Ligands books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Serotonin Receptors and their Ligands

Serotonin Receptors and their Ligands

File Size : 67,67 MB
Total View : 1319 Views
DOWNLOAD

An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin recep

Serotonin Receptors in Neurobiology

Serotonin Receptors in Neurobiology

File Size : 55,55 MB
Total View : 6251 Views
DOWNLOAD

A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subje

The Serotonin Receptors

The Serotonin Receptors

File Size : 84,84 MB
Total View : 758 Views
DOWNLOAD

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug

5-HT2B Receptors

5-HT2B Receptors

File Size : 59,59 MB
Total View : 5742 Views
DOWNLOAD

This contributed volume provides a comprehensive assessment of the roles played by 5-HT2B receptors in humans. These receptors have been shown to play an import