SIRT6 Activities in DNA Damage Repair and Premature Aging

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  • SIRT6 Activities in DNA Damage Repair and Premature Aging Book Detail

  • Author : Shrestha Ghosh
  • Release Date : 2019-08-30
  • Publisher : Springer Nature
  • Genre : Medical
  • Pages : 151
  • ISBN 13 : 9813292679
  • File Size : 83,83 MB

SIRT6 Activities in DNA Damage Repair and Premature Aging by Shrestha Ghosh PDF Summary

Book Description: This book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging. It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant implications in devising therapeutic strategies to combat age-associated pathologies. Given its scope, the book offers a valuable resource for students and researchers in the fields of genetics, cell biology, molecular biology etc.

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DNA Damage, DNA Repair and Disease

DNA Damage, DNA Repair and Disease

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The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, prot