Comprehensive Analysis of Parasite Biology

Released on by Sylke Müller
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  • Comprehensive Analysis of Parasite Biology Book Detail

  • Author : Sylke Müller
  • Release Date : 2016-10-10
  • Publisher : John Wiley & Sons
  • Genre : Medical
  • Pages : 574
  • ISBN 13 : 3527339043
  • File Size : 97,97 MB
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Comprehensive Analysis of Parasite Biology by Sylke Müller PDF Summary

Book Description: Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

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