The Epigenome and Developmental Origins of Health and Disease

Released on by Cheryl S. Rosenfeld
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  • The Epigenome and Developmental Origins of Health and Disease Book Detail

  • Author : Cheryl S. Rosenfeld
  • Release Date : 2015-10-10
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 562
  • ISBN 13 : 0128016728
  • File Size : 4,4 MB
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The Epigenome and Developmental Origins of Health and Disease by Cheryl S. Rosenfeld PDF Summary

Book Description: Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field

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Developmental Origins of Health and Disease

Developmental Origins of Health and Disease

File Size : 30,30 MB
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This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound conse

Epigenetics

Epigenetics

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WHAT IS EPIGENETICS? Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA seq