The Extracellular Matrix: an Overview

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  • The Extracellular Matrix: an Overview Book Detail

  • Author : Robert Mecham
  • Release Date : 2011-02-16
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 429
  • ISBN 13 : 3642165559
  • File Size : 29,29 MB

The Extracellular Matrix: an Overview by Robert Mecham PDF Summary

Book Description: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

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The Extracellular Matrix: an Overview

The Extracellular Matrix: an Overview

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Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the s

Extracellular Matrix in Development

Extracellular Matrix in Development

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Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process i