The Proteasome in Neurodegeneration

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In the last 50 years a wealth of information has allowed us to understand the contribution of various regulatory factors that alter mRNA and protein s- thesis t

Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System

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Proteolysis by the ubiquitin-proteasome pathway (UPP) in the nervous system has been extensively studied both in the context of normal physiological function as

The Role of the Ubiquitin-proteasome System in Neurodegenerative Disorders

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Pesticides and Proteasome Inhibition in Neurodegeneration Associated with Parkinson's Disease

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Quality Control of Cellular Protein in Neurodegenerative Disorders

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Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondri