Thermodynamics and Kinetics of Drug Binding

Released on by György Keserü
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  • Thermodynamics and Kinetics of Drug Binding Book Detail

  • Author : György Keserü
  • Release Date : 2015-07-28
  • Publisher : John Wiley & Sons
  • Genre : Medical
  • Pages : 360
  • ISBN 13 : 3527673040
  • File Size : 61,61 MB
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Thermodynamics and Kinetics of Drug Binding by György Keserü PDF Summary

Book Description: This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.

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