Small Molecules in Oncology

Released on by Uwe M. Martens
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  • Small Molecules in Oncology Book Detail

  • Author : Uwe M. Martens
  • Release Date : 2014-04-22
  • Publisher : Springer Science & Business
  • Genre : Medical
  • Pages : 418
  • ISBN 13 : 3642544908
  • File Size : 3,3 MB
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Small Molecules in Oncology by Uwe M. Martens PDF Summary

Book Description: Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

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