Viral Proteases and Their Inhibitors

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  • Viral Proteases and Their Inhibitors Book Detail

  • Author : Satya Prakash Gupta
  • Release Date : 2017-07-03
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 518
  • ISBN 13 : 0128096829
  • File Size : 36,36 MB

Viral Proteases and Their Inhibitors by Satya Prakash Gupta PDF Summary

Book Description: Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases

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Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors

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Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As informa

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Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

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This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the f

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A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has be